Researchers at Duke-NUS Medical School discovered that physical activity reduces DEAF1 gene expression, enabling older muscles to repair damage and maintain strength. The finding provides a mechanistic explanation for why exercise combats age-related muscle decline.
Science Daily · Monday, 6 July 2026
Researchers have uncovered a molecular “switch” that helps explain why exercise keeps ageing muscles healthy. By reducing levels of a gene called DEAF1, physical activity allows older muscles to clear out damage, repair themselves, and maintain strength.
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